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Single particle analysis of manganese-induced prion protein aggregates

✍ Scribed by Johannes Levin; Uwe Bertsch; Hans Kretzschmar; Armin Giese


Book ID
116290115
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
399 KB
Volume
329
Category
Article
ISSN
0006-291X

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## Purpose To evaluate the potential of fluorescence single particle tracking (fSPT) for the characterization of submicron protein aggregates in human serum, plasma and formulations containing human serum albumin (HSA). ## Methods A monoclonal IgG was covalently labeled with a fluorescent dye and