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Using Theory and Simulation to Understand Permeation and Selectivity in Ion Channels

✍ Scribed by Eric Jakobsson


Book ID
115638878
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
204 KB
Volume
14
Category
Article
ISSN
1046-2023

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Modeling of ion permeation in calcium an
✍ P.S. Raj Ganesh; Baron Chanda; S.K. Gupta; M.K. Mathew; Jayaraman Chandrasekhar πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 193 KB πŸ‘ 1 views

## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr