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Selectivity and Permeation in Calcium Release Channel of Cardiac Muscle: Alkali Metal Ions

✍ Scribed by Chen, Duan P.; Xu, Le; Tripathy, Ashutosh; Meissner, Gerhard; Eisenberg, Bob


Book ID
119412280
Publisher
Biophysical Society
Year
1999
Tongue
English
Weight
292 KB
Volume
76
Category
Article
ISSN
0006-3495

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## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr