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Mechanisms of Permeation and Selectivity in Calcium Channels

โœ Scribed by Corry, Ben; Allen, Toby W.; Kuyucak, Serdar; Chung, Shin-Ho

Book ID
118037302
Publisher
Biophysical Society
Year
2001
Tongue
English
Weight
316 KB
Volume
80
Category
Article
ISSN
0006-3495

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## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr