Mechanism of ion permeation through calcium channels
β Scribed by Hess, Peter; Tsien, Richard W.
- Book ID
- 109735643
- Publisher
- Nature Publishing Group
- Year
- 1984
- Tongue
- English
- Weight
- 456 KB
- Volume
- 309
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/309453a0
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π SIMILAR VOLUMES
A Ca 2+ current activated by store depletion has been described recently in several cell types and has been termed/CRAC (for Ca 2+ release-activated Ca 2+ current). In this paper, the Ca 2+ and Ba 2+ permeability of CRAC channels is investigated in mast cells, rat basophilic leukaemia cells (RBL) an
## Structure-function studies have shown that it is possible to convert a sodium channel to a calcium-selective channel by a single amino acid substitution in the selectivity filter locus. Ion permeation through the "model selectivity filter" was modeled with a reduced set of functional groups repr