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Using structure to define the function of phosphoinositide 3-kinase family members

✍ Scribed by J. Domin; M.D. Waterfield


Book ID
117107738
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
522 KB
Volume
410
Category
Article
ISSN
0014-5793

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A member of a new class of protein tyrosine kinases, JAK1, has been mapped to lp31.3 by in situ hybridization and Southern blot analysis of a panel of mouse-human hybrid cell lines. A murine protein tyrosine kinase, related to, but distinct, from JAK1, was mapped by in situ hybridization to human Ch