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The HSV-1 Us3 protein kinase is sufficient to block apoptosis induced by overexpression of a variety of Bcl-2 family members

✍ Scribed by Paul D Ogg; Peter J McDonell; Brent J Ryckman; C.Michael Knudson; Richard J Roller

Book ID
113945767
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
1001 KB
Volume
319
Category
Article
ISSN
0042-6822

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## Abstract ## Objective Rheumatoid arthritis (RA) synovial hyperplasia is related in part to a resistance to apoptosis exhibited by fibroblast‐like synoviocytes (FLS). Since hypoxia is a regulator of apoptosis, and since RA synovium is hypoxic, we conducted this study to examine the effects of hy