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Uses of 2-diazo-4,5,6,7-tetrahydrobenzo[b]thiophene derivatives in the synthesis of azoles, azines, and their fused derivatives

✍ Scribed by Wagnat W. Wardakhan; Daisy H. Fleita

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 167 KB
Volume: 13
Category: Article
ISSN: 1042-7163
DOI: 10.1002/hc.10003

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✦ Synopsis

Abstract

The reactions of 2‐diazo‐4,5,6,7‐tetrahydrobenzo[b]thiophene derivatives with dimeric adducts 2a and 2b gave the hydrazone derivatives 3a and 3b, respectively. The reactivity of the latter products towards various chemical reagents was studied in order to provide azole and azine derivatives incorporating the thiophene ring, and most of them showed high antimicrobial activity. © 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:108–115, 2002; Published online in Wiley Interscience (www.interscience.wiley.com). DOI 10.1002/hc.10003

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