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Usefulness of chaotropic salt additive in RP-HPLC of organic nonionized compounds

✍ Scribed by Flieger, Jolanta; Siwek, Agata; Pizoń, Magdalena

Book ID: 118763506
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 1002 KB
Volume: 36
Category: Article
ISSN: 1615-9306
DOI: 10.1002/jssc.201200798

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## Abstract The use of gradient elution in RP‐HPLC is increasing. Aqueous buffers, such as phosphate at pH 1.7, with acetonitrile as the organic modifier are particularly advantageous as eluents with linear elution strength (LES). In the isocratic mode, under the experimental conditions used, fairl