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Use of the N-tosyl-activated aziridine 1,2-dideoxy-1,2-iminomannitol as a synthon for 1-deoxymannojirimycin analogues

✍ Scribed by Gert J Joly; Koen Peeters; Hua Mao; Thierry Brossette; Georges J Hoornaert; Frans Compernolle


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
111 KB
Volume
41
Category
Article
ISSN
0040-4039

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Ethyl N-(o-Ethynyl)malonanilide as a Useful Building Block for the Preparation of 3,4-Disubstituted-2(1H)-quinolones, 3,4-Disubstituted- and2,3,4-Trisubstituted Quinolines. -The Pd-catalyzed reaction of the o-ethynylmalonanilides with aryl halides affords disubstituted alkynes. Following intramolecu