𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Use of recombinant human α2-adrenoceptors to characterize subtype selectivity of antagonist binding

✍ Scribed by Anne Marjamäki; Kirsti Luomala; Sari Ala-Uotila; Mika Scheinin

Book ID
113398463
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
627 KB
Volume
246
Category
Article
ISSN
0922-4106

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Subtype-specific stimulation of [35S]GTP
Subtype-specific stimulation of [35S]GTPγS binding by recombinant α2-adrenoceptors
✍ Juha M. Peltonen; Marjo Pihlavisto; Mika Scheinin 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 99 KB

We measured agonist-stimulated binding of the stable GTP-analog guanosine-5'-O-(3-[35S]thiotriphosphate) ([35S]GTPgammaS) as a functional assay to monitor G-protein activation by recombinant human alpha2-adrenoceptor subtypes alpha2A, alpha2B and alpha2C. (-)-Noradrenaline was a full agonist in all