Use of heptakis(2,6-di-O-methyl)-β-cyclodextrin in on-line capillary zone electrophoresis-mass spectrometry for the chiral separation of ropivacaine
✍ Scribed by M.H. Lamoree; A.F.H. Sprang; U.R. Tjaden; J. van der Greef
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 474 KB
- Volume
- 742
- Category
- Article
- ISSN
- 1873-3778
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The single isomer, fully and permanently charged heptakis-2,3-di-. methyl-6-sulfato --cyclodextrin was used to study the complexation behavior of the enantiomers of noncharged analytes in capillary electrophoresis. Separation selectivities were calculated from the measured effective mobilities and
## Abstract The enantiomeric separation of a series of basic pharmaceuticals (β‐blockers, local anesthetics, sympathomimetics) has been investigated in nonaqueous capillary electrophoresis (NACE) systems using heptakis(2,3‐di‐__O__‐methyl‐6‐__O__‐sulfo)‐β‐cyclodextrin (HDMS‐β‐CD) in combination wit
## Abstract The characteristics of the new chiral stationary phase heptakis(2,3‐di‐__O__‐methyl‐6‐__O__‐__tert__‐butyldimethylsilyl)‐β‐cyclodextrin are outlined and compared with permethyl‐ and perethyl‐β‐cyclodextrins.