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Use of Cigarette-Smoking History to Estimate the Likelihood of Mutations in Epidermal Growth Factor Receptor Gene Exons 19 and 21 in Lung Adenocarcinomas

✍ Scribed by Pham, D.


Book ID
118039969
Publisher
American Society of Clinical Oncology
Year
2006
Tongue
English
Weight
132 KB
Volume
24
Category
Article
ISSN
0732-183X

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## Abstract The presence of activating mutations within the tyrosine kinase domain of the epidermal growth factor receptor gene has been attributed to a positive response to biological therapy of lung cancer by small‐molecular tyrosine kinase inhibitors, gefitinib and erlotinib. Among the two most