## Abstract We investigated the relationships between genetic factors and clinical outcome in Japanese nonβsmallβcell lung cancer (NSCLC) patients treated with gefitinib. Ninetyβeight NSCLC patients who had been treated with gefitinib, were screened for mutations in epidermal growth factor receptor
Dose effect of cigarette smoking on frequency and spectrum of epidermal growth factor receptor gene mutations in Korean patients with non-small cell lung cancer
β Scribed by Young Joo Lee; Hyo Sub Shim; Young Ae Kang; Su Jung Hong; Hyun Ki Kim; Hoguen Kim; Se Kyu Kim; Sung Ho Choi; Joo-Hang Kim; Byoung Chul Cho
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 358 KB
- Volume
- 136
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Dear Sir
## Abstract ## Background and Objectives In this paper we examined the influence of epidermal growth factor receptor (EGFR) gene mutations on EGFR expression, downstream mediators, and survival in patients with nonβsmall cell lung cancer (NSCLC). ## Methods We retrospectively analyzed the tumors
## Abstract ## BACKGROUND. Because the investigation of epidermal growth factor receptor gene (__EGFR__) status as a predictor of gefitinib efficacy in Japanese patients has shown promise, the authors evaluated __EGFR__ mutations and gene amplification in biopsy specimens from Japanese patients wi