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The usefulness of mutation-specific antibodies in detecting epidermal growth factor receptor mutations and in predicting response to tyrosine kinase inhibitor therapy in lung adenocarcinoma

✍ Scribed by Kozu, Yoshiki; Tsuta, Koji; Kohno, Takashi; Sekine, Ikuo; Yoshida, Akihiko; Watanabe, Shunichi; Tamura, Tomohide; Yokota, Jun; Suzuki, Kenji; Asamura, Hisao; Furuta, Koh; Tsuda, Hitoshi


Book ID
119320497
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
753 KB
Volume
73
Category
Article
ISSN
0169-5002

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Epidermal growth factor receptor mutatio
✍ Victor Cohen; Jason S. Agulnik; Celina Ang; Goulnar Kasymjanova; Gerald Batist; πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 206 KB πŸ‘ 1 views

## Abstract ## BACKGROUND: Somatic mutations in the epidermal growth factor receptor (EGFR) kinase domain are associated with sensitivity to EGFR‐tyrosine kinase inhibitors (EGFR‐TKI) in patients with nonsmall cell lung cancer (NSCLC). ## METHODS: The authors tested the possibility that nucleoti