Use of chiral and achiral ion-pairing reagents in combination with cyclodextrins in capillary electrophoresis
β Scribed by Thomas Jira; Antje Bunke; Astrid Karbaum
- Book ID
- 108341321
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 416 KB
- Volume
- 798
- Category
- Article
- ISSN
- 1873-3778
No coin nor oath required. For personal study only.
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Enantioseparation of thalidomide and its hydroxylated metabolites using capillary electrophoresis with various cyclodextrins and their combinations as chiral buffer additives The separation of thalidomide (TD) and its hydroxylated metabolites including their simultaneous enantioseparation was studi
The influence of the choice of type and/or concentration of cyclodextrin, other additives, the temperature surrounding the capillary, and buffer pH on the separation of some chiral basic drug substances in capillary zone electrophoresis has been evaluated. It was found that pH of the buffer and type