The enantiomeric separation of a series of acidic pharmaceuticals (mostly nonsteroidal anti-inflammatory drugs) has been investigated in NACE systems using single-isomer amino beta-CD derivatives. The first part of this study consisted of the selection of the basic experimental conditions to separat
✦ LIBER ✦
Synergistic effects of ion-pairing in the enantiomeric separation of basic compounds with cyclodextrin derivatives in nonaqueous capillary electrophoresis
✍ Scribed by Anne-Catherine Servais; Marianne Fillet; Adel M. Abushoffa; Philippe Hubert; Jacques Crommen
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 98 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0173-0835
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## Abstract The enantiomeric separation of a series of basic pharmaceuticals (β‐blockers, local anesthetics, sympathomimetics) has been investigated in nonaqueous capillary electrophoresis (NACE) systems using heptakis(2,3‐di‐__O__‐methyl‐6‐__O__‐sulfo)‐β‐cyclodextrin (HDMS‐β‐CD) in combination wit