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Use of cationic cyclodextrin for enantioseparation by capillary electrophoresis

✍ Scribed by Antje Bunke; Thomas Jira


Book ID
108341327
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
274 KB
Volume
798
Category
Article
ISSN
1873-3778

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## Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis The racemates of several chiral thiobarbiturates were separated by using different cyclodextrins in capillary electrophoresis (CE). Six neutral and negatively charged cyclodextrins 1 (CDs) were em

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## Abstract A sulfated β‐cyclodextrin (sulfated β‐CD)‐mediated capillary electrophoresis method is described for the enantioseparation of cetirizine using achiral cefazolin as an internal standard. The enantioseparation of the drug was performed in a borate buffer (5 mM, pH 8.7) with 1% sulfated β‐