Use of capillary electrophoresis-electrospray ionization mass spectrometry in the analysis of synthetic peptides
β Scribed by Kenneth J. Rosnack; Justin G. Stroh; David H. Singleton; Bradley C. Guarino; Glenn C. Andrews
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 576 KB
- Volume
- 675
- Category
- Article
- ISSN
- 1873-3778
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## Abstract In the present work, an exhaustive review of the main developments and applications of CEβMS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, onβchip applications as well as other
Capillary zone electrophoresis (CZE) coupled with an on-line mass spectrometric (MS) detection system by an atmospheric pressure electrospray ionization (ESI) interface has been used successfully for separations of peptide and protein mixtures. For CZE-MS, ESI produces multiply charged molecular ion