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Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia

✍ Scribed by Michael J. Mann; Elaine Tseng; Mark Ratcliffe; Greg Strattman; Anil De Silva; Teresa DeMarco; Nancy Achorn; William Moskalik; Charles Hoopes

Book ID: 116518036
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 85 KB
Volume: 24
Category: Article
ISSN: 1557-3117
DOI: 10.1016/j.healun.2003.11.401

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Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrom