✦ LIBER ✦

Report of successful use of argatroban as an alternative anticoagulant during coronary stent implantation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome

✍ Scribed by Lewis, Bruce E. ;Iaffaldano, Robert ;McKiernan, Thomas L. ;Rao, Luxman ;Donkin, Jocelyn ;Wallenga, Jeanine M.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 351 KB
Volume: 38
Category: Article
ISSN: 0098-6569
DOI: 10.1002/(sici)1097-0304(199606)38:2<206::aid-ccd20>3.0.co;2-f

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✦ Synopsis

Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrombin agents represent treatment alternatives in HITTS patients who require anticoagulation. We report successful coronary stent implantation in a HITTS patient using the antithrombin agent argatroban. c 19% WIIO~-LIOB. Inc.