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Successful use of fondaparinux in a patient with a mechanical heart valve replacement and a history of heparin-induced thrombocytopenia

✍ Scribed by Tia L. Corbett; Kathy S. Elher; Candice L. Garwood


Publisher
Springer US
Year
2010
Tongue
English
Weight
108 KB
Volume
30
Category
Article
ISSN
0929-5305

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Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrom