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Use of 3-azabicyclo[3.2.2]nonane in the mannich reaction IV. Additional derived products

✍ Scribed by C. Dewitt Blanton Jr; W. Lewis Nobles


Publisher
John Wiley and Sons
Year
1964
Tongue
English
Weight
208 KB
Volume
53
Category
Article
ISSN
0022-3549

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## Abstract The double Mannich reaction of cyclic β‐keto esters with bis(alkoxymethyl)alkylamines provides an efficient and versatile method for the construction of azabicyclo[3.3.1]nonanes and azabicyclo[3.2.1]octanes. The optimum conditions for efficient reaction involve use of the activator tric