Use of 3-azabicyclo[3.2.2]nonane in the mannich reaction IV. Additional derived products
β Scribed by C. Dewitt Blanton Jr; W. Lewis Nobles
- Publisher
- John Wiley and Sons
- Year
- 1964
- Tongue
- English
- Weight
- 208 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3549
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π SIMILAR VOLUMES
methyl group in the 6 position of the tetracycline molecule. While DMCT has not been reported to have been tested in the chemotherapy of leptospirosis, chlortetracycline (CT) , oxytetracycline (OT). and tetracycline (TC) have been effective against experimental leptospiral infections in chick embryo
## Abstract The double Mannich reaction of cyclic Ξ²βketo esters with bis(alkoxymethyl)alkylamines provides an efficient and versatile method for the construction of azabicyclo[3.3.1]nonanes and azabicyclo[3.2.1]octanes. The optimum conditions for efficient reaction involve use of the activator tric