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Use of 2,2′-dithiobis(5-nitropyridine) for the heterodimerization of cysteine containing peptides. Introduction of the 5-nitro-2-pyridinesulfenyl group

✍ Scribed by Francesc Rabanal; William F. DeGrado; P.Leslie Dutton


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
308 KB
Volume
37
Category
Article
ISSN
0040-4039

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A method for the facile removal of the t-butoxycarbonyl (Boc) group with aluminum chloride during solidphase oligonucleotide synthesis is presented The method enables the common amino protecting group, which is stable to base and weak acid, to be removed with no threat to the integrity of the oligon