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Ursodeoxycholic acid for primary biliary cirrhosis: final results of a 12-year, prospective, randomized, controlled trial

✍ Scribed by George V Papatheodoridis; Emilia S Hadziyannis; Melanie Deutsch; Stephanos J Hadziyannis


Book ID
119392548
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
92 KB
Volume
97
Category
Article
ISSN
0002-9270

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Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h