A two year controlled trial examining the effectiveness of ursodeoxycholic acid in primary biliary cirrhosis
β Scribed by IAN B. TURNER; MARGARET MYSZOR; HARRIET C. MITCHISON; MARK K. BENNETT; ALISTAIR D. BURT; OLIVER F. W. JAMES
- Book ID
- 118704359
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 639 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0815-9319
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π SIMILAR VOLUMES
One hundred fifty-one patients with primary biliary cirrhosis (PBC) grouped into four strata based on entry serum bilirubin (<2 mg/dL vs. 2 mg/dL or greater) and liver histology (stages I, 1 1 vs. stages 111, IV-Ludwig criteria) were randomized within each stratum to ursodiol or placebo given in a s
Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h