Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis
โ Scribed by RE Poupon; KD Lindor; K Cauch-Dudek; ER Dickson; R Poupon; EJ Heathcote
- Book ID
- 118519870
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 354 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0016-5085
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๐ SIMILAR VOLUMES
The efficacy of colchicine combined with ursodeoxycholic acid (UDCA) and UDCA alone in the treatment of patients with nonadvanced primary biliary cirrhosis (PBC) was evaluated in a 2-year controlled study. Seventy-four patients with PBC who had been treated previously with UDCA (at least 8 months) b
One hundred fifty-one patients with primary biliary cirrhosis (PBC) grouped into four strata based on entry serum bilirubin (<2 mg/dL vs. 2 mg/dL or greater) and liver histology (stages I, 1 1 vs. stages 111, IV-Ludwig criteria) were randomized within each stratum to ursodiol or placebo given in a s
Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile acids are retained in the liver and are hepatotoxic. Ursodeoxycholic acid is the least-known hepatotoxic bile acid, h