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UROKINASE-TYPE PLASMINOGEN ACTIVATOR ANTIGEN AND EARLY RELAPSE IN BREAST CANCER

✍ Scribed by Janicke, Fritz; Schmitt, Manfred; Ulm, Klaus; Gössner, Wolfgang; Graeff, Henner

Book ID
122814238
Publisher
The Lancet
Year
1989
Tongue
English
Weight
170 KB
Volume
334
Category
Article
ISSN
0140-6736

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d