Urokinase plasminogen activator and urok
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C. Duggan; T. Maguire; E. McDermott; N. O'Higgins; J. J. Fennelly; M. J. Duffy
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Article
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1995
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John Wiley and Sons
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French
β 385 KB
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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d