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Urokinase plasminogen activator and prognosis in breast cancer

✍ Scribed by DUFFY, M

Book ID
122923345
Publisher
The Lancet
Year
1990
Tongue
English
Weight
182 KB
Volume
335
Category
Article
ISSN
0140-6736

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Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d