Urinary metabolites of caffeine in the premature infant
β Scribed by R. Gorodischer; E. Zmora; Z. Ben-Zvi; D. Warszwaski; A. Yaari; S. Sofer; M. J. Arnaud
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 213 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0031-6970
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Fifty spontaneously breathing, preterm infants 48 h old, of 32 weeks' gestation or less, were assigned randomly to receive caffeine citrate (loading dose 20 mg/kg, maintenance dose 10 mg/kg per day) or a placebo (NaCl 0.9%). The study hypothesis was that caffeine reduces the proportion of infants wi
The present study was undertaken to establish normal values of the N 'methylhistidine to creatinine excretion ratio in very premature infants, to observe changes with postnatal age, and to determine whether or not reliable data on this index of myofibrillar protein breakdown could be obtained from u