Urinary caffeine metabolites in man
✍ Scribed by D. Ullrich; D. Compagnone; B. Münch; A. Brandes; H. Hille; J. Bircher
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 804 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The human urinary metabolism of two pyrazolone derivatives, morazone and famprofazone, has been investigated. After administration of morazone, the metabolites p-hydroxymorazone and phenazone-4-carboxylic acid were excreted in addition to the known metabolite, phenmetrazine, and unchanged morazone.
CYPIA2 is a cytochrome P450 which is inducible by polycyclic aromatic hydrocarbons. This induction could be mediated via the Ah locus, which encodes a cytosolic receptor responsible for the regulation of the CYPIA1 gene. Enzyme activity in vivo can be measured by the urinary caffeine metabolite rati
The urinary metabolites of p-phenoxyphenol methanesulfonate ( I ) in rat and man were characterired. The drug was extensively nietabolired in both cpecies and excreted mainly in the form of conjugated phenolic compounds. The major metabolite of I in both species was identified as the conjugated mono