𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Some new urinary metabolites of famprofazone and morazone in man

✍ Scribed by Michael Neugebauer


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
613 KB
Volume
2
Category
Article
ISSN
0731-7085

No coin nor oath required. For personal study only.

✦ Synopsis


The human urinary metabolism of two pyrazolone derivatives, morazone and famprofazone, has been investigated. After administration of morazone, the metabolites p-hydroxymorazone and phenazone-4-carboxylic acid were excreted in addition to the known metabolite, phenmetrazine, and unchanged morazone. Meta~lism of famprofazone led to the formation of methamphetamine; the pyrazolone moiety was excreted as 3-hydroxymethyl-propyphenazone.


πŸ“œ SIMILAR VOLUMES


Identification of urinary metabolites of
✍ F. F. Sun πŸ“‚ Article πŸ“… 1973 πŸ› John Wiley and Sons 🌐 English βš– 381 KB

The urinary metabolites of p-phenoxyphenol methanesulfonate ( I ) in rat and man were characterired. The drug was extensively nietabolired in both cpecies and excreted mainly in the form of conjugated phenolic compounds. The major metabolite of I in both species was identified as the conjugated mono