Urinary epidermal growth factor receptor-binding growth factors in patients with cancers of the digestive tract
✍ Scribed by Lea-Yea Chuang; Wen-Chun Hung; Mei-Li Yang; Chun-Chang Chang; Jung-Fa Tsai
- Book ID
- 107740542
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 589 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0009-9120
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Bladder cancers frequently exhibit an increased number of epidermal growth factor receptors (EGFR) in comparison to normal urothelium. The EGFR could potentially be a target for toxic conjugates. The aim of our study was to compare the expression of EGFR in metastases with concurrent or primary tumo
## Abstract ## BACKGROUND. Cleavage of membrane‐anchored heparin‐binding epidermal growth factor‐like growth factor (proHB‐EGF) yields a soluble HB‐EGF isoform (sHB‐EGF), which is an activating epidermal growth factor receptor (EGFR) ligand and a C‐terminal fragment HB‐EGF‐C acting directly in the