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Uptake of Glutamate and Cystine in C-6 Glioma Cells and in Cultured Astrocytes

✍ Scribed by Yukie Cho; Shiro Bannai


Book ID
111175862
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
760 KB
Volume
55
Category
Article
ISSN
0022-3042

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To test the hypothesis that clozapine-induced reduction of glutamate transporter-1 (GLT-1) expression is mediated by astrocytes, we studied the effects of clozapine on Glu transporters and Glu uptake in primary astrocyte cultures of the cerebral cortex. Astrocyte cultures treated for 48 h with cloza