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Uptake of adenosine by isolated bovine cortex microvessels

โœ Scribed by V. Stefanovich


Publisher
Springer
Year
1983
Tongue
English
Weight
779 KB
Volume
8
Category
Article
ISSN
0364-3190

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Uptake of propranolol by microvessels is
โœ Atsushi Kurihara; Hiroshi Suzuki; Yasufumi Sawada; Yuichi Sugiyama; Tatsuji Iga; ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 552 KB

To study the transport system of propranolol (PL), a basic drug, in the blood-brain barrier, the uptake of PL into isolated bovine brain microvessels was investigated. The uptake of PL was a concentrative one via saturable process (Km = 42.5 microM) that was decreased by hypothermia (Q10 = 2.2), but