To study the transport system of propranolol (PL), a basic drug, in the blood-brain barrier, the uptake of PL into isolated bovine brain microvessels was investigated. The uptake of PL was a concentrative one via saturable process (Km = 42.5 microM) that was decreased by hypothermia (Q10 = 2.2), but
โฆ LIBER โฆ
Mechanism of valproic acid uptake by isolated rat brain microvessels
โ Scribed by Kohji Naora; Danny D. Shen
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 830 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0920-1211
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