✦ LIBER ✦

Update on BRCA1 and BRCA2: molecular biology and genetics

✍ Scribed by B.L. Weber

Book ID: 117667837
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 163 KB
Volume: 35
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(99)81298-2

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## Abstract Women with a mutation in __BRCA1__ or __BRCA2__ face a lifetime risk of breast cancer of ∼80%, and following the first diagnosis the10‐year risk of contralateral breast cancer is ∼30%. It has been shown that both tamoxifen and oophorectomy prevent contralateral breast cancer, but it is