BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

Maximising survival: The main concern of

Maximising survival: The main concern of women with hereditary breast and ovarian cancer who undergo genetic testing for BRCA1/2

✍ Jeffers, Lisa; Morrison, Patrick J.; McCaughan, Eilis; Fitzsimons, Donna 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 307 KB

Differences in the frequency and distrib

Differences in the frequency and distribution of BRCA1 and BRCA2 mutations in breast/ovarian cancer cases from the Basque country with respect to the Spanish population: implications for genetic counselling

✍ E. Beristain; C. Martínez-Bouzas; I. Guerra; N. Viguera; J. Moreno; E. Ibañez; J 📂 Article 📅 2007 🏛 Springer US 🌐 English ⚖ 237 KB

Genetic variants and haplotype analyses

Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families

✍ Sylvie Desjardins; Pascal Belleau; Yvan Labrie; Geneviève Ouellette; Paul Besset 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 214 KB 👁 1 views

## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa

Evaluating the performance of the breast

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

✍ Fischer, Christine (author);Kuchenbäcker, Karoline (author);Engel, Christoph (au 📂 Article 📅 2013 🏛 BMJ Publishing Group 🌐 English ⚖ 172 KB

Evaluating the performance of the breast

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

✍ Fischer, Christine (author);Kuchenbäcker, Karoline (author);Engel, Christoph (au 📂 Article 📅 2013 🏛 BMJ Publishing Group 🌐 English ⚖ 172 KB

Novel and recurrentBRCA1/BRCA2mutations

Novel and recurrentBRCA1/BRCA2mutations in early onset and familial breast and ovarian cancer detected in the Program of Genetic Counseling in Cancer of Valencian Community (eastern Spain). Relationship of family phenotypes with mutation prevalence

✍ Juan JimÃ©nez, Inmaculada; GarcÃa Casado, Zaida; Palanca Suela, Sarai; Esteban 📂 Article 📅 2013 🏛 Springer Netherlands 🌐 English ⚖ 304 KB