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BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

✍ Scribed by Welcsh, P. L.


Book ID
118253916
Publisher
Oxford University Press
Year
2001
Tongue
English
Weight
383 KB
Volume
10
Category
Article
ISSN
0964-6906

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## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa