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Novel and recurrentBRCA1/BRCA2mutations in early onset and familial breast and ovarian cancer detected in the Program of Genetic Counseling in Cancer of Valencian Community (eastern Spain). Relationship of family phenotypes with mutation prevalence

✍ Scribed by Juan Jiménez, Inmaculada; García Casado, Zaida; Palanca Suela, Sarai; Esteban Cardeñosa, Eva; López Guerrero, José Antonio; Segura Huerta, Ángel; Chirivella González, Isabel; Sánchez Heras, Ana Beatriz; Juan Fita, Mª José; Tena García, Isabel; Guillen Ponce, Carmen; Martínez de Dueñas, Eduardo; Romero Noguera, Ignacio; Salas Trejo, Dolores; Goicoechea Sáez, Mercedes; Bolufer Gilabert, Pascual


Book ID
120253480
Publisher
Springer Netherlands
Year
2013
Tongue
English
Weight
304 KB
Volume
12
Category
Article
ISSN
1389-9600

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Prevalence of BRCA1 genomic rearrangemen
✍ Simona Agata; Alessandra Viel; Lara Della Puppa; Laura Cortesi; Giusi Fersini; M 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 164 KB 👁 1 views

The presence of genomic rearrangements of the BRCA1 gene in breast and/or ovarian cancer families has been intensively investigated in patients from various countries over the last years. A number of different rearrangements have been reported by several studies that clearly document the involvement