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An Update on DNA-Based BRCA1/BRCA2 Genetic Counseling in Hereditary Breast Cancer

✍ Scribed by Henry T Lynch; Patrice Watson; Susan Tinley; Carrie Snyder; Carolyn Durham; Jane Lynch; Yulia Kirnarsky; Olga Serova; Gilbert Lenoir; Caryn Lerman; Steven A Narod

Book ID
114136837
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
203 KB
Volume
109
Category
Article
ISSN
0165-4608

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## Abstract Women with a mutation in __BRCA1__ or __BRCA2__ face a lifetime risk of breast cancer of ∼80%, and following the first diagnosis the10‐year risk of contralateral breast cancer is ∼30%. It has been shown that both tamoxifen and oophorectomy prevent contralateral breast cancer, but it is