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Up-regulation of the betaine/GABA transporter BGT1 by JAK2

✍ Scribed by Zohreh Hosseinzadeh; Manzar Shojaiefard; Shefalee K. Bhavsar; Florian Lang


Book ID
116303138
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
494 KB
Volume
420
Category
Article
ISSN
0006-291X

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✍ Xiao-Ming Zhu; Wei-Yi Ong πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 461 KB

## Abstract The γ‐aminobutyric acid (GABA) transporters GAT‐1, GAT‐2, GAT‐3, and BGT‐1 have been cloned and identified according to their differential amino acid sequences and pharmacologic properties. In contrast to GAT‐1, ‐2, or ‐3, BGT‐1 is capable of utilizing both GABA and betaine as substrate