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Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy

✍ Scribed by Arne Schousboe; Orla M. Larsson; Alan Sarup; H. Steve White

Book ID
113584894
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
145 KB
Volume
500
Category
Article
ISSN
0014-2999

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Changes in GABA transporters in the rat
Changes in GABA transporters in the rat hippocampus after kainate-induced neuronal injury: Decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1
✍ Xiao-Ming Zhu; Wei-Yi Ong πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 461 KB

## Abstract The γ‐aminobutyric acid (GABA) transporters GAT‐1, GAT‐2, GAT‐3, and BGT‐1 have been cloned and identified according to their differential amino acid sequences and pharmacologic properties. In contrast to GAT‐1, ‐2, or ‐3, BGT‐1 is capable of utilizing both GABA and betaine as substrate