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Up-Regulation of miR-182 Expression after Epigenetic Modulation of Human Melanoma Cells

✍ Scribed by Suhu Liu MD, PhD,Paul M. Howell BS,Adam I. Riker MD, FACS

Book ID
126393760
Publisher
Springer
Year
2012
Tongue
English
Weight
703 KB
Volume
20
Category
Article
ISSN
1068-9265

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## Abstract The intratumoral heterogeneity of cancer testis antigens (CTA) expression, which is driven by promoter methylation status, may hamper the effectiveness of CTA‐directed vaccination of melanoma patients. Thus, we investigated whether the intratumoral heterogeneity of CTA expression is inh