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Unstable trinucleotide repeats and the diagnosis of neurodegenerative disease

โœ Scribed by Harry T. Orr

Book ID
116083577
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
574 KB
Volume
25
Category
Article
ISSN
1532-8392

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New hopes for cloning susceptibility genes for schizophrenia and bipolar affective disorder followed the discovery of a novel type of DNA mutation, namely unstable DNA. One class of unstable DNA, trinucleotide repeat expansion, is the causal mutation in myotonic dystrophy, fragile X mental retardati