✦ LIBER ✦

Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomes

✍ Scribed by Haber, Daniel A.; Schimke, Robert T.

Book ID: 123232489
Publisher: Elsevier Science
Year: 1981
Tongue: English
Weight: 870 KB
Volume: 26
Category: Article
ISSN: 0092-8674
DOI: 10.1016/0092-8674(81)90204-X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Chromosome-mediated transfer and amplifi

Chromosome-mediated transfer and amplification of an altered mouse dihydrofolate reductase gene

✍ Daniel A. Haber; Robert T. Schimke 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 752 KB

Replication of the dihydrofolate reducta

Replication of the dihydrofolate reductase genes on double minute chromosomes in a murine cell line

✍ Thea D. Tlsty; Paula Adams 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 720 KB

MYC gene amplification in double minute

MYC gene amplification in double minute chromosomes in an aggressive large B-cell lymphoma with leukemic presentation: a case report

✍ F. Alseraye; R. Padmore; M. Wozniak; J. McGowan-Jordan 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 168 KB

Amplification of the c-myc Oncogene is a

Amplification of the c-myc Oncogene is associated with an abnormally banded region on chromosome 8 or double minute chromosomes in two HL-60 human leukemia sublines

✍ Shinichi Misawa; Stephen P. Staal; Joseph R. Testa 📂 Article 📅 1987 🏛 Elsevier Science 🌐 English ⚖ 705 KB

Amplification on double-minute chromosom

Amplification on double-minute chromosomes and partial-tandem duplication of the MILL gene in leukemic cells of a patient with acute myelogenous leukemia

✍ Yoji Ariyama; Yoji Fukuda; Yoshiaki Okuno; Masao Seto; Kose Date; Tatsuo Abe; Yu 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 588 KB

Amplification of the MLL gene on double

Amplification of the MLL gene on double minutes, a homogeneously staining region, and ring chromosomes in five patients with acute myeloid leukemia or myelodysplastic syndrome

✍ Berthold Streubel; Peter Valent; Ulrich Jäger; Martin Edelhäuser; Hannes Wandt; 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 184 KB 👁 2 views

Gene amplification is one of the mechanisms for activating proto-oncogenes resulting in an enhanced expression of the corresponding gene product. By fluorescence in situ hybridization (FISH), amplification of the proto-oncogene MLL has been described only in seven patients with acute myeloid leukemi