Amplification of the MLL gene on double
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Berthold Streubel; Peter Valent; Ulrich JΓ€ger; Martin EdelhΓ€user; Hannes Wandt;
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Article
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2000
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John Wiley and Sons
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English
β 184 KB
π 2 views
Gene amplification is one of the mechanisms for activating proto-oncogenes resulting in an enhanced expression of the corresponding gene product. By fluorescence in situ hybridization (FISH), amplification of the proto-oncogene MLL has been described only in seven patients with acute myeloid leukemi