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Occurrence of T-cell lymphoma in a patient with philadelphia chromosome-positive chronic myelogenous leukemia with rearrangements of BCR and TCR-β genes in the lymph nodes

✍ Scribed by Pauline Tittley; Jean Marc Trempe; Richard van der Jagt; Jeanne Drouin; Lothar Huebsch; Bill McLeish; Gregory Cheng


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
250 KB
Volume
42
Category
Article
ISSN
0361-8609

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✍ Alvaro Aguayo; Jorge E. Cortes; Hagop M. Kantarjian; Miloslav Beran; Varsha Gand 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## BACKGROUND. T-cell lymphoid blastic phase (BP) transformation is rare in chronic myelogenous leukemia (CML). 2-amino-9-␤-D-arabinosyl-6-methoxy-9H-guanine (GW506U78), a prodrug of arabinosylguanine (ara-G), is effective in T-cell leukemias. ## METHODS. The authors present a case of a 48-year