Unique variations of Epstein–Barr virus-encoded BARF1 gene in nasopharyngeal carcinoma biopsies
✍ Scribed by Yun Wang; Xiao-Feng Wang; Zhi-Fu Sun; Bing Luo
- Book ID
- 116968820
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 427 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0168-1702
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The BARF1 gene is located in the BamHI-A fragment of the Epstein-Barr virus (EBV) genome, encodes 221 amino acids, and has activity as an oncogene. Several reports have demonstrated that BARF1 is expressed in the tissues of various EBV-associated epithelioid malignancies. However,BARF1 is thought to
## Abstract Nasopharyngeal carcinoma (NPC) is the most prevalent ENT‐tumour in Indonesia. We investigated the primary diagnostic value of Epstein‐Barr virus (EBV) DNA load and mRNA detection in noninvasive nasopharyngeal (NP) brushings, obtained prospectively from consecutive Indonesian ENT‐patient