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Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma

✍ Scribed by Susanna H Hutajulu; Eveline K Hoebe; Sandra AWM Verkuijlen; Jajah Fachiroh; Bambang Hariwijanto; Sofia M Haryana; Servi JC Stevens; Astrid E Greijer; Jaap M Middeldorp

Book ID
119911544
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
957 KB
Volume
5
Category
Article
ISSN
1750-9378

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Epstein–Barr virus (EBV)-encoded BARF1 g
Epstein–Barr virus (EBV)-encoded BARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression
✍ Eri Seto; Lixin Yang; Jaap Middeldorp; Tzung-Shiahn Sheen; Jen-Yan Chen; Masashi 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB

The BARF1 gene is located in the BamHI-A fragment of the Epstein-Barr virus (EBV) genome, encodes 221 amino acids, and has activity as an oncogene. Several reports have demonstrated that BARF1 is expressed in the tissues of various EBV-associated epithelioid malignancies. However,BARF1 is thought to